Case 35: Pathology

Excellent work, your patient tolerated the kidney biopsy well. It’s the day afterwards and your pathologist shows you the PAS stain below.  Click here for a few quick pathology tips.


Which of the following do you see below?
Thickened glomerular basement membrane
Correct! The basement membrane of this glomerulus appears thicker than normal.
Neutrophils within capillary loops
Though the capillary loops appear rigid and thickened, we do not see any neutrophils or inflammatory cells within them.
Podocyte effacement
The podocyte structure is best visualized under electron microscopy, not light microscopy.
Subepithelial deposits
Subepithelial deposits are best seen under electron microscopy, not light microscopy.

Your pathologist tells you other stains will take 1-2 more days…

Click here when you’re ready to look at more stains that might help you narrow down your differential diagnosis!

Case 35 Index
Case 35 Introduction
Case 35 Physical Exam
Case 35 Diagnostic Testing